There's this quote from Daniel Handler I used on a library poster once that I forget exactly now, but it's something like "You never love a book the way you love a book when you're ten." I've always wondered if people just won't appreciate Wrinkle enough if they don't read it as a misfit ten-year-old girl! That connection really makes it for me. But then again, it was all grown-ups who gave it the Newbery, so I suppose it might not be NECESSARY.